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After 16 weeks, all animals were challenged by intratracheal instillation of nontypeable Haemophilus influenzae (NTHI), an opportunistic gram-negative bacterium responsible for respiratory tract infections and exacerbations in COPD patients [23], and euthanized 0, 4, and 12 h later

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"Instead of slaying his tormentor, he was more likely to resolve matters ambiguously by deftly discarding his still burning butt," author Richard Kluger in his book about the history of cigarettes, "Ashes to Ashes" (via Tough Without a Gun)

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